Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973600 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL4230728 | 0.99 | SMN1; SMN2 (0.97) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL4235238 | 0.94 | SMN1; SMN2 (0.89) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL5864233 | 0.93 | SMN1; SMN2 (0.86) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL13647686 | 0.89 | SMN1; SMN2 (0.80) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL4235113 | 0.88 | SMN1; SMN2 (0.78) | SMN1; SMN2KMT2AMEN1GAACASP1 | |
| SCHEMBL9201916 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AMEN1GAAHSD17B10 | |
| SCHEMBL11033307 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AMEN1GAAHSD17B10 | |
| SCHEMBL11724761 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AMEN1GAAHSD17B10 | |
| SCHEMBL8335250 | 0.87 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1GAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009027-B2 | Graft polymers formed by using polyesterimides having cyclic dicarboxylic anhydride end groups; blends used to form carpet filaments or fibers | THUERINGISCHES INSTITUT FUER TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2006-03-07 | — | — | US | claimed |
| EP-1339773-B1 | METHOD FOR PRODUCING MELTABLE POLYESTERS | THUERINGISCHES INST TEXTIL (DE) | 2005-02-02 | — | — | EP | claimed |
| US-20040039137-A1 | Graft polymers formed by using polyesterimides having cyclic dicarboxylic anhydride end groups; blends used to form carpet filaments or fibers | THUERINGISCHES INSTITUT FUER TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2004-02-26 | — | — | US | claimed |
| EP-1339773-A2 | METHOD FOR PRODUCING MELTABLE POLYESTERS | THÜRINGISCHES INSTITUT FÜR TEXTIL- UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2003-09-03 | — | — | EP | claimed |
| WO-2002042353-A2 | METHOD FOR PRODUCING MELTABLE POLYESTERS | THÜRINGISCHES INSTITUT FÜR TEXTIL - UND KUNSTSTOFF - FORSCHUNG E.V. (DE) | 2002-05-30 | — | — | WO | claimed |
| EP-2008674-B1 | Catheters and Catheter shafts made from liquid crystal polymer blends | BOSTON SCIENT LTD (BB) | 2012-03-14 | — | — | EP | disclosed |
| US-20090215814-A1 | Method of inhibiting neurotrophin-receptor binding | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-08-27 | — | — | US | disclosed |
| EP-2008674-A1 | Balloons made from liquid crystal polymer blends | Boston Scientific Limited (BB) | 2008-12-31 | — | — | EP | disclosed |
| EP-1467776-B1 | BALLOONS MADE FROM LIQUID CRYSTAL POLYMER BLENDS | BOSTON SCIENT LTD (BB) | 2008-10-08 | — | — | EP | disclosed |
| US-20070078137-A1 | Method of inhibiting neurotrophin-receptor binding | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-04-05 | — | — | US | disclosed |
| US-7148352-B2 | Method of inhibiting neurotrophin-receptor binding | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2006-12-12 | — | — | US | disclosed |
| US-7009027-B2 | Graft polymers formed by using polyesterimides having cyclic dicarboxylic anhydride end groups; blends used to form carpet filaments or fibers | THUERINGISCHES INSTITUT FUER TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2006-03-07 | — | — | US | disclosed |
| US-20030138577-A1 | Balloons made from liquid crystal polymer blends | BOSTON SCIENTIFIC SCIMED, INC. | 2003-07-24 | — | — | US | disclosed |
| US-6468990-B1 | ADMINISTERING COMPOUNDS HAVING ELECTRONEGATIVE GROUPS WHICH INTERACT WITH CERTAIN LYSINE RESIDUES IN NERVE GROWTH FACTOR AND/OR HYDROPHOBIC MOIETY WHICH INTERACTS WITH HYDROPHOBIC REGION FORMED BY CERTAIN ISOLEUCINE AND PHENYLALANINE RESIDUES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-10-22 | — | — | US | disclosed |
| EP-1226121-A1 | METHOD OF INHIBITING NEUROTROPHIN-RECEPTOR BINDING | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-07-31 | — | — | EP | disclosed |
| WO-2002042353-A2 | METHOD FOR PRODUCING MELTABLE POLYESTERS | THÜRINGISCHES INSTITUT FÜR TEXTIL - UND KUNSTSTOFF - FORSCHUNG E.V. (DE) | 2002-05-30 | — | — | WO | disclosed |
| WO-2000069829-A1 | METHOD OF INHIBITING NEUROTROPHIN-RECEPTOR BINDING | QUEEN'S UNIVERSITY (CA) | 2000-11-23 | — | — | WO | disclosed |
| US-5994284-A | REACTING PHTHALIC ACID OR ANHYDRIDE WITH CAPROLACTAM; OXIDATION WITH HYDROGEN PEROXIDE | CLARIANT GMBH (DE) | 1999-11-30 | — | — | US | disclosed |
| US-4388456-A | FOOD PACKAGING | EASTMAN KODAK COMPANY (US) | 1983-06-14 | — | — | US | disclosed |
| US-4041065-A | WIRE COATINGS, FILMS, MOLDINGS | STANDARD OIL COMPANY (INDIANA) (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215814-A1 | Method of inhibiting neurotrophin-receptor binding | NGF, NTRK2, BDNF | SMN1; SMN2 707/4885KMT2A 3466/4885MEN1 3489/4885 |
| US-20070078137-A1 | Method of inhibiting neurotrophin-receptor binding | NGF, NTRK2, BDNF | SMN1; SMN2 707/4885KMT2A 3466/4885MEN1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.