Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.55 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.55 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | BHMT | Q93088 | 3/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033390 | 1.00 | GRIK1 (0.55) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL4677572 | 0.81 | ARG1 (0.52) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL10187369 | 0.80 | NOS2 (0.50) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL1553985 | 0.79 | ARG1 (0.50) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL27932283 | 0.79 | ARG1 (0.50) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL18788686 | 0.79 | ARG1 (0.53) | GRIK1GRIK2GRM1GRM2ARG1 | |
| SCHEMBL2781165 | 0.79 | ARG1 (0.53) | GRIK1GRIK2GRM1GRM2ARG1 | |
| Carbocysteine SCHEMBL20854 | 0.79 | BHMT (0.59) | GRIK1GRIK2GRM1GRM2ARG1 | |
| Carbocysteine SCHEMBL9236855 | 0.79 | BHMT (0.59) | GRIK1GRIK2GRM1GRM2ARG1 | |
| Carbocysteine SCHEMBL69149 | 0.79 | BHMT (0.59) | GRIK1GRIK2GRM1GRM2ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539320-A | COSMETICS | L'OREAL (FR) | 1985-09-03 | — | — | US | disclosed |
| US-4483983-A | Substituted derivatives of thiamorpholinone | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-11-20 | — | — | US | disclosed |