O-Xylene

O-Xylene

SCHEMBL11033426

CC(C)CO.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ACHE P22303 2/20 0.56
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
TRPA1 O75762 4/20 0.43
ALDH1A1 P00352 2/20 0.39
P2RX7 Q99572 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL8391796 1.00 TSHR (0.56) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL11032683 1.00 TSHR (0.56) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL11035318 1.00 TSHR (0.56) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL11403331 0.86 ACHE (0.53) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL9150349 0.85 ALDH1A1 (0.44) TSHRACHEKDM4ECYP1A2TRPA1
Toluene SCHEMBL744674 0.81 TSHR (0.58) TSHRACHEKDM4ETRPA1ALDH1A1
O-Xylene SCHEMBL27667248 0.81 CYP1A2 (0.59) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL8092002 0.80 TSHR (0.59) TSHRACHECYP1A2TRPA1ALDH1A1
O-Xylene SCHEMBL80205 0.79 ACHE (0.67) TSHRACHEKDM4ECYP1A2TRPA1
O-Xylene SCHEMBL1019179 0.79 ACHE (0.67) TSHRACHEKDM4ECYP1A2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487674-A USING RESIN AND SURFACTANT DRESSER INDUSTRIES, INC. (US) 1984-12-11 US disclosed