O-Xylene

O-Xylene

SCHEMBL8092002

CCC(C)C.Cc1ccccc1C

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
ACHE P22303 2/20 0.59
MAOA P21397 3/20 0.40
MAOB P27338 2/20 0.40
ALDH1A1 P00352 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
ESR1 P03372 1/20 0.39
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
SCN4A P35499 3/20 0.37
CYP1A2 P05177 3/20 0.37
TRPA1 O75762 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27888742 0.83 TSHR (0.53) TSHRACHEMAOAMAOBALDH1A1
O-Xylene SCHEMBL27796014 0.83 TSHR (0.53) TSHRACHEMAOAMAOBLMNA
O-Xylene SCHEMBL21715160 0.81 ACHE (0.50) TSHRACHEMAOAMAOBALDH1A1
Toluene SCHEMBL8151758 0.80 LMNA (0.61) TSHRACHEMAOAALDH1A1LMNA
O-Xylene SCHEMBL8391796 0.80 TSHR (0.56) TSHRACHEMAOAMAOBALDH1A1
O-Xylene SCHEMBL11035318 0.80 TSHR (0.56) TSHRACHEMAOAMAOBALDH1A1
O-Xylene SCHEMBL11032683 0.80 TSHR (0.56) TSHRACHEMAOAMAOBALDH1A1
O-Xylene SCHEMBL11033426 0.80 TSHR (0.56) TSHRACHEMAOAMAOBALDH1A1
Toluene SCHEMBL5025517 0.80 LMNA (0.61) TSHRACHEMAOAALDH1A1LMNA
Toluene SCHEMBL8159259 0.80 LMNA (0.61) TSHRACHEMAOAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1277211-A Molecular weight of polymer produced by single-point catalyst control and method of molecular weight distrubution UNION CARBIDE CHEM PLASTIC (US) 2000-12-20 CN claimed
EP-1054025-A1 Method for controlling molecular weight and molecular weight distribution in polymers produced using a single site catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-11-22 EP claimed
CN-1277211-A Molecular weight of polymer produced by single-point catalyst control and method of molecular weight distrubution UNION CARBIDE CHEM PLASTIC (US) 2000-12-20 CN disclosed
EP-1054025-A1 Method for controlling molecular weight and molecular weight distribution in polymers produced using a single site catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-11-22 EP disclosed