Styrene

Styrene

SCHEMBL11033522

C=Cc1ccccc1.CC(C)N(C)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TSHR P16473 1/20 0.58
KDM4E B2RXH2 1/20 0.39
AHR P35869 1/20 0.39
PTGS2 P35354 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.38
AOC3 Q16853 1/20 0.37
CYP3A4 P08684 1/20 0.37
RELA Q04206 1/20 0.36
HDAC8 Q9BY41 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6808124 0.85 ALDH1A1 (0.61) ALDH1A1TSHRKDM4EAHRPTGS2
Styrene SCHEMBL9467161 0.84 ALDH1A1 (0.74) ALDH1A1TSHRKDM4EAHRPTGS2
Styrene SCHEMBL27201704 0.82 ALDH1A1 (0.78) ALDH1A1TSHRAHRPTGS2TDP1
Styrene SCHEMBL2862346 0.82 ALDH1A1 (0.78) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL28134369 0.82 ALDH1A1 (0.78) ALDH1A1TSHRAHRPTGS2TDP1
Styrene SCHEMBL27910207 0.80 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL28019103 0.80 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL1567316 0.80 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL27887859 0.79 ALDH1A1 (0.82) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL6829874 0.79 ALDH1A1 (0.82) ALDH1A1TSHRTDP1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP claimed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US claimed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP claimed
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP disclosed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US disclosed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed