Styrene

Styrene

SCHEMBL6808124

C=Cc1ccccc1.CC(C)N(C)C(C)C

nearest known ligand 0.61

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TSHR P16473 1/20 0.61
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
RELA Q04206 1/20 0.38
HDAC8 Q9BY41 2/20 0.37
KDM4E B2RXH2 1/20 0.36
AHR P35869 1/20 0.36
PTGS2 P35354 1/20 0.36
HTR2A P28223 3/20 0.34
AOC3 Q16853 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11033522 0.85 ALDH1A1 (0.58) ALDH1A1TSHRTP53TDP1RELA
Styrene SCHEMBL2862346 0.84 ALDH1A1 (0.78) ALDH1A1TSHRTP53TDP1RELA
Styrene SCHEMBL28134369 0.84 ALDH1A1 (0.78) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL27201704 0.84 ALDH1A1 (0.78) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL27910207 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1RELA
Styrene SCHEMBL28019103 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1RELA
Styrene SCHEMBL1567316 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1RELA
Styrene SCHEMBL9467161 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL27353595 0.79 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL27612971 0.79 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0864592-B1 DIENE RUBBER ZEON CORP (JP) 2004-09-22 EP disclosed
US-6211321-B1 CONTAINING A TERTIARY AMINO-CONTAINING VINYL MONOMER AND A HALOGEN CONTAINING VONYL MONOMER NIPPON ZEON CO., LTD. (JP) 2001-04-03 US disclosed
EP-0864592-A1 DIENE RUBBER NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed