⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692743 | 0.79 | — | — | |
| SCHEMBL1923313 | 0.74 | — | — | |
| SCHEMBL9491545 | 0.70 | — | — | |
| SCHEMBL11461175 | 0.70 | TSHR (0.43) | — | |
| SCHEMBL6836191 | 0.69 | LMNA (0.39) | — | |
| SCHEMBL21785 | 0.67 | — | — | |
| SCHEMBL27912543 | 0.67 | — | — | |
| SCHEMBL6244874 | 0.65 | LDHA (0.37) | — | |
| SCHEMBL1749997 | 0.65 | — | — | |
| SCHEMBL6836206 | 0.65 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500717-A | Process for preparation of 2-oxazolidinones | THE DOW CHEMICAL COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4209628-A | FROM CARBON DIOXIDE AND AN AZIRIDINE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 1980-06-24 | — | — | US | disclosed |