SCHEMBL6836191

SCHEMBL6836191

NC(=O)NNCCNNC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
TSHR P16473 2/20 0.39
NFKB1 P19838 2/20 0.39
CYP1A2 P05177 2/20 0.39
THPO P40225 2/20 0.39
CYP3A4 P08684 2/20 0.39
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
CRBN Q96SW2 1/20 0.32
TDP1 Q9NUW8 3/20 0.31
ALDH1A1 P00352 2/20 0.31
OR51E2 Q9H255 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6836206 0.88 TSHR (0.35) LMNATSHRNFKB1CYP1A2THPO
SCHEMBL3441219 0.85 MAOA (0.38) LMNATSHRNFKB1CYP1A2THPO
SCHEMBL7615594 0.85
SCHEMBL2961180 0.83
SCHEMBL1662264 0.83 CA12 (0.50) LMNATSHRCYP1A2THPOPMP22
SCHEMBL11015165 0.81 LMNA (0.38) LMNATSHRNFKB1CYP1A2THPO
Bicarbonate SCHEMBL10712563 0.81 LDHA (0.32) LMNATSHRNFKB1CYP1A2THPO
SCHEMBL11293176 0.79
SCHEMBL1516248 0.79 MAOA (0.34) CYP1A2CYP3A4MAOAMAOBKDM4E
Hydrazine SCHEMBL11766600 0.79 LMNA (0.36) LMNATSHRNFKB1CYP1A2THPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753363-B1 BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY POLYPLASTICS CO., LTD. (JP) 2004-06-22 US disclosed
EP-0671423-B1 Thermosetting one-component-polyurethane reactive masses and use thereof BAYER AG (DE) 1999-05-06 EP disclosed
US-5574123-A CURES WITHOUT BLISTERS EVEN AFTER STORAGE BAYER AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
EP-0671423-A1 Process for the preparation of thermosetting one-component-polyurethane reactive masses BAYER AG (DE) 1995-09-13 EP disclosed
US-5159011-A Textile wet strength BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US disclosed
EP-0467168-A2 Aqueous preparations from copolymer latices and polyisocyanate dispersions BASF Aktiengesellschaft (DE) 1992-01-22 EP disclosed
EP-0204970-B1 PROCESS FOR THE PREPARATION OF STABLE DISPERSIONS OF PARTICULATE POLYISOCYANATES, AND THEIR USE BASF Aktiengesellschaft (DE) 1990-12-27 EP disclosed
US-4888124-A TREATING WITH POLYAMINE, MILLING TO FORM POLYUREA SHELL ON SURFACE OF PARTICLES BASF AKTIENGESELLSCHAFT (DE) 1989-12-19 US disclosed
US-4849262-A Pigment printing pastes and dyeing liquors containing stable dispersions of finely divided solid polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1989-07-18 US disclosed
EP-0153579-B1 USE OF THERMOSETTING POLYURETHANE UREA REACTIVE MASSES OF ADHESIVES BAYER AG (DE) 1989-06-14 EP disclosed
EP-0165437-A1 Process for the preparation of solid polyisocyanates having a delayed reactivity, dispersed polyisocyanates enveloped by polymers, and their use BAYER AG (DE) 1985-12-27 EP disclosed
EP-0162364-A2 Process for the preparation of deactivated suspensions of small polyisocyanate particles in higher molecular compounds, deactivated suspensions and their use in polyurethane preparation BAYER AG (DE) 1985-11-27 EP disclosed
US-4546165-A Process for the production of stabilized polyisocyanates of retarded reactivity and their use in the production of polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1985-10-08 US disclosed
EP-0153579-A2 Use of thermosetting polyurethane urea reactive masses of adhesives BAYER AG (DE) 1985-09-04 EP disclosed
EP-0150803-A2 PVC-plastisols for coating applications containing adhesion improving additives and their use BAYER AG (DE) 1985-08-07 EP disclosed
EP-0150790-A2 Process for preparing stabilized polyisocyanates, stabilized isocyanates with delayed reactivity and their use in polyurethane preparation BAYER AG (DE) 1985-08-07 EP disclosed
US-4483974-A POLYMERIZATION INHIGITION BY BLOCKING WITH AMINE, HYDRAZINE, OR HYDRAZIDE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-20 US disclosed
EP-0103323-A2 Process for the preparation of stabilized polyisocyanates, stabilized polyisocyanates having retarded reactivity and their use in the preparation of polyurethanes BAYER AG (DE) 1984-03-21 EP disclosed
US-4286014-A CHAIN EXTENDER COMPRISING HYDRAZINE OR DERIVATIVE TORAY INDUSTRIES, INCORPORATED (JP) 1981-08-25 US disclosed
US-4069377-A Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes PENNWALT CORPORATION 1978-01-17 US disclosed