Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030920 | 0.96 | CASP3 (0.45) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11031707 | 0.95 | CASP3 (0.44) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11032654 | 0.95 | CASP3 (0.44) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11033832 | 0.92 | MAPT (0.46) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11032794 | 0.89 | MAPT (0.46) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11032301 | 0.88 | MAPT (0.42) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11031324 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11032326 | 0.86 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL10581494 | 0.85 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11032728 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479885-A | Phthalonitrile derivatives and a liquid crystal composition containing the same | HITACHI, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |