Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033840 | 0.92 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11030920 | 0.90 | CASP3 (0.45) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11031707 | 0.89 | CASP3 (0.44) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11032654 | 0.89 | CASP3 (0.44) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11034014 | 0.87 | PDE3A (0.43) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11031805 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11035312 | 0.86 | MAPT (0.41) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL10581653 | 0.85 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7574828 | 0.84 | KMT2A (0.55) | MAPTALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11033841 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479885-A | Phthalonitrile derivatives and a liquid crystal composition containing the same | HITACHI, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0087963-A2 | Phthalonitrile derivatives and liquid crystal compositions containing them | Hitachi, Ltd. (JP) | 1983-09-07 | — | — | EP | disclosed |