Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962424 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL8827913 | 0.77 | ALDH1A1 (0.70) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL1710000 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL11749330 | 0.76 | ALDH1A1 (0.77) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL9803958 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL11742390 | 0.74 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL17997163 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL13344784 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL14288405 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL10731214 | 0.72 | ALDH1A1 (0.62) | ALDH1A1LMNAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562138-A | Nitrogen-containing heterocyclic blocked mercapto development inhibitors | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-12-31 | — | — | US | disclosed |