Styrene

Styrene

SCHEMBL11033987

C=Cc1ccccc1.CCCNCC

nearest known ligand 0.54

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TSHR P16473 2/20 0.54
HTT P42858 1/20 0.39
ADRB2 P07550 1/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
SIGMAR1 Q99720 2/20 0.34
LMNA P02545 1/20 0.34
EGFR P00533 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC8 Q9BY41 2/20 0.33
PRMT6 Q96LA8 1/20 0.33
HTR1B P28222 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8063766 0.92 ALDH1A1 (0.58) ALDH1A1TSHRTP53TDP1TAS1R3
Styrene SCHEMBL523206 0.88 ALDH1A1 (0.64) ALDH1A1TSHRHTTADRB2TP53
Styrene SCHEMBL10628538 0.82 ALDH1A1 (0.56) ALDH1A1TSHRTP53TDP1TAS1R3
Styrene SCHEMBL93585 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1TAS1R3
Styrene SCHEMBL290213 0.81 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1TAS1R3
Styrene SCHEMBL8073549 0.81 TSHR (0.54) ALDH1A1TSHRHTTTDP1SIGMAR1
Styrene SCHEMBL6811672 0.79 ALDH1A1 (0.64) ALDH1A1TSHRTP53TDP1TAS1R3
Styrene SCHEMBL10628603 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTP53TDP1SIGMAR1
Dipentylamine SCHEMBL5492942 0.79 SIGMAR1 (0.58) ALDH1A1TSHRTDP1SIGMAR1LMNA
Styrene SCHEMBL8515568 0.79 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP disclosed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US disclosed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed