Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010987 | 0.84 | KDM4E (0.39) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL11034287 | 0.84 | PDE5A (0.40) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL11007618 | 0.84 | PDE5A (0.31) | ALDH1A1HPGDPDE5AKDM4EUSP2 | |
| SCHEMBL11007368 | 0.81 | FGFR1 (0.38) | ALDH1A1HPGDTP53SMN1; SMN2PDE5A | |
| SCHEMBL11007757 | 0.80 | MAPT (0.34) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL11010240 | 0.78 | AMY1A (0.34) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL11009397 | 0.78 | PDE5A (0.35) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL11011531 | 0.73 | FGFR1 (0.38) | ALDH1A1HPGDMEN1KMT2APDE5A | |
| SCHEMBL11005174 | 0.73 | PDE5A (0.32) | ALDH1A1PDE5AFGFR1FGFR2TSHR | |
| SCHEMBL11011418 | 0.73 | PDE5A (0.32) | ALDH1A1PDE5AFGFR1FGFR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142075-A2 | Purine derivatives, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |