SCHEMBL455718

SCHEMBL455718

CCCCOC(=O)C(CC)(CC)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
ATM Q13315 1/20 0.45
HCAR2 Q8TDS4 3/20 0.44
TSHR P16473 5/20 0.42
HPGD P15428 1/20 0.42
NAAA Q02083 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
EPHX1 P07099 1/20 0.37
LMNA P02545 1/20 0.37
ESR1 P03372 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPK1 P28482 1/20 0.37
CYP2C19 P33261 1/20 0.37
NR1H2 P55055 1/20 0.37
RNASEL Q05823 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ACHE P22303 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034348 0.94 NAAA (0.47) ALDH1A1ATMHCAR2TSHRNAAA
SCHEMBL9815160 0.92 NAAA (0.50) ALDH1A1HCAR2TSHRNAAAEPHX1
SCHEMBL9472810 0.92 NAAA (0.50) ALDH1A1HCAR2TSHRNAAAEPHX1
SCHEMBL7687966 0.92 NAAA (0.50) ALDH1A1HCAR2TSHRNAAAEPHX1
SCHEMBL7681803 0.92 NAAA (0.50) ALDH1A1HCAR2TSHRNAAAEPHX1
SCHEMBL11540502 0.92 NAAA (0.50) ALDH1A1HCAR2TSHRNAAAEPHX1
SCHEMBL6048843 0.90 ALDH1A1 (0.54) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL452622 0.88 HCAR2 (0.41) ALDH1A1HCAR2TSHRTDP1LMNA
SCHEMBL31462326 0.86 ALDH1A1 (0.47) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL27434075 0.84 ALDH1A1 (0.48) ALDH1A1ATMHCAR2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
JP-8269036-A None JP disclosed
US-20240191594-A1 Cement Top Jobs In Wellbore Annuli Using Expandable Compositions CHEVRON U.S.A. INC. 2024-06-13 US disclosed
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20240026749-A1 DEPLOYMENT METHODS FOR EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20240026206-A1 METHODS OF USING EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20230233500-A1 Gasdermin D (GSDMD) Succination for the Treatment of Inflammatory Disease UNIVERSITY OF MASSACHUSETTS 2023-07-27 US disclosed
CN-116474766-A Cerium oxide loaded manganese-zinc oxide catalyst, preparation method and method for preparing malonate derivative by using cerium oxide loaded manganese-zinc oxide catalyst 万华化学集团股份有限公司 2023-07-25 CN disclosed
US-4990479-A Coordination catalysts MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0385765-A2 Process for polymerizing olefins and catalyst for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-05 EP disclosed
EP-0350170-A2 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-01-10 EP disclosed
US-4804756-A Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones ORTHO PHARMACEUTICAL CORPORATION (US) 1989-02-14 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed
US-4751304-A Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones ORTHO PHARMACEUTICAL CORPORATION (US) 1988-06-14 US disclosed
EP-0179303-A1 Catalysts for the polymerization of olefins Himont Incorporated (US) 1986-04-30 EP disclosed
EP-0177256-A2 Process for preparing 5,6-dialkoxy-4-alkyl-2(1h)-quinazolinones ORTHO PHARMACEUTICAL CORPORATION (US) 1986-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 ALDH1A1 654/4885ATM 3981/4885HCAR2 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.