Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11034985 | 0.99 | OPRD1 (0.52) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| Pibaxizine SCHEMBL1231070 | 0.97 | OPRD1 (0.51) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| Pibaxizine SCHEMBL11033265 | 0.96 | OPRD1 (0.50) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| SCHEMBL11037158 | 0.93 | HTR2A (0.52) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11034935 | 0.92 | HRH1 (0.59) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| SCHEMBL11037025 | 0.91 | HRH1 (0.56) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11035289 | 0.89 | HRH1 (0.57) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11034928 | 0.89 | DRD3 (0.50) | OPRD1OPRM1OPRK1HRH1HTR2A | |
| SCHEMBL11035757 | 0.88 | HRH1 (0.48) | OPRD1OPRM1OPRK1HRH1SLC6A2 | |
| SCHEMBL11034834 | 0.87 | OPRD1 (0.52) | OPRD1OPRM1OPRK1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | claimed |
| US-4443460-A | ANTIALLERGENS, ANTIHISTAMINES, ANTISPASMODICS, BRONCHODILATORS | UCB, SOCIETE ANONYME (BE) | 1984-04-17 | — | — | US | disclosed |