Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11034791 | 0.99 | HRH1 (0.49) | HRH1DRD3SLC6A2HRH2HTR2A | |
| SCHEMBL11099119 | 0.91 | OPRM1 (0.44) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL11034451 | 0.90 | HPGD (0.46) | HRH1DRD3SLC6A2HRH2HTR2A | |
| SCHEMBL11034385 | 0.88 | OPRD1 (0.53) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL11034985 | 0.87 | OPRD1 (0.52) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Pibaxizine SCHEMBL1231070 | 0.86 | OPRD1 (0.51) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL11034935 | 0.85 | HRH1 (0.59) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Pibaxizine SCHEMBL11033265 | 0.84 | OPRD1 (0.50) | HRH1DRD3SLC6A2HRH2HTR2A | |
| SCHEMBL11037025 | 0.84 | HRH1 (0.56) | HRH1DRD3SLC6A2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL11035289 | 0.83 | HRH1 (0.57) | HRH1DRD3SLC6A2HRH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443460-A | ANTIALLERGENS, ANTIHISTAMINES, ANTISPASMODICS, BRONCHODILATORS | UCB, SOCIETE ANONYME (BE) | 1984-04-17 | — | — | US | disclosed |