Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11034648 | 0.99 | OPRD1 (0.51) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| SCHEMBL11034679 | 0.93 | OPRK1 (0.49) | OPRD1OPRM1OPRK1P2RX7DRD2 | |
| SCHEMBL11036099 | 0.91 | DRD2 (0.55) | OPRD1OPRM1OPRK1P2RX7TACR1 | |
| SCHEMBL11097971 | 0.91 | OPRD1 (0.51) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| Pibaxizine SCHEMBL1231070 | 0.90 | OPRD1 (0.51) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| Hydrochloric Acid SCHEMBL11036480 | 0.90 | OPRD1 (0.50) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| Pibaxizine SCHEMBL11033265 | 0.89 | OPRD1 (0.50) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| SCHEMBL11037592 | 0.89 | OPRD1 (0.52) | OPRD1OPRM1OPRK1SETD7DRD2 | |
| Hydrochloric Acid SCHEMBL11037583 | 0.88 | OPRD1 (0.51) | OPRD1OPRM1OPRK1DRD2HTR2A | |
| SCHEMBL11034385 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1OPRK1P2RX7SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | claimed |
| EP-0048705-A1 | 2-(4-(Diphenylmethylene)-1-piperidinyl)-acetic acids and their amides, their preparation and pharmaceutical preparations containing them | U C B, S.A. (BE) | 1982-03-31 | — | — | EP | claimed |
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | disclosed |
| US-4443460-A | ANTIALLERGENS, ANTIHISTAMINES, ANTISPASMODICS, BRONCHODILATORS | UCB, SOCIETE ANONYME (BE) | 1984-04-17 | — | — | US | disclosed |
| EP-0048705-A1 | 2-(4-(Diphenylmethylene)-1-piperidinyl)-acetic acids and their amides, their preparation and pharmaceutical preparations containing them | U C B, S.A. (BE) | 1982-03-31 | — | — | EP | disclosed |