Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154019 | 0.87 | GLA (0.53) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL9900679 | 0.84 | ALDH1A1 (0.48) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL28248372 | 0.83 | HTR2B (0.54) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL28865565 | 0.83 | HTR2B (0.50) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL595713 | 0.83 | GLA (0.54) | GLAFFAR1FFAR4MEP1AMEP1B | |
| SCHEMBL24358855 | 0.82 | HTR2B (0.49) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL6950852 | 0.82 | TSHR (0.52) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL29732423 | 0.82 | HTR2B (0.49) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL5643624 | 0.81 | MEN1 (0.52) | GLACNR1KCNJ1KCNH2FFAR1 | |
| SCHEMBL320197 | 0.80 | HRH3 (0.49) | GLACNR1KCNJ1KCNH2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517197-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1985-05-14 | — | — | US | disclosed |