Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154019 | 0.94 | GLA (0.53) | TSHRFFAR1FFAR4MAOAMAOB | |
| SCHEMBL6962952 | 0.92 | DRD2 (0.49) | TSHRFFAR1FFAR4MAOAMAOB | |
| SCHEMBL6951637 | 0.90 | FAAH (0.50) | TSHRFFAR1FFAR4MAOAMAOB | |
| SCHEMBL6960752 | 0.90 | FAAH (0.50) | TSHRFFAR1FFAR4MAOAMAOB | |
| SCHEMBL9900679 | 0.86 | ALDH1A1 (0.48) | FFAR1FFAR4MAOAMAOBALDH1A1 | |
| SCHEMBL28248372 | 0.85 | HTR2B (0.54) | FFAR1FFAR4MAOAMAOBALDH1A1 | |
| SCHEMBL28865565 | 0.85 | HTR2B (0.50) | FFAR1FFAR4MAOAMAOBALDH1A1 | |
| SCHEMBL7450600 | 0.84 | CLK4 (0.50) | MAOBALDH1A1GLAMEN1KMT2A | |
| SCHEMBL24358855 | 0.83 | HTR2B (0.49) | TSHRFFAR1FFAR4GLAKCNJ1 | |
| SCHEMBL29732423 | 0.83 | HTR2B (0.49) | TSHRFFAR1FFAR4GLAKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10449174-B2 | Aryl isonitrile compounds as a new class of potent, broad-spectrum antifungal compounds | PURDUE RESEARCH FOUNDATION (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | PURDUE RESEARCH FOUNDATION (US) | 2017-06-29 | — | — | US | disclosed |
| CN-106190930-A | One strain lactobacillus delbruockii subspecies bulgaricus MGA17 6 and application thereof | 内蒙古农业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-102726455-A | Botanical nematocide and preparation method thereof | DAQING COLLEGE HEILONGJIANG ACADEMY OF SCIENCE | 2012-10-17 | — | — | CN | disclosed |
| EP-0711762-B1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10449174-B2 | Aryl isonitrile compounds as a new class of potent, broad-spectrum antifungal compounds | AHR, CYP3A4, NAT1 | TSHR 3640/4885FFAR1 2450/4885FFAR4 1177/4885 |
| US-20170181997-A1 | ARYL ISONITRILE COMPOUNDS AS A NEW CLASS OF POTENT, BROAD-SPECTRUM ANTIFUNGAL COMPOUNDS | AHR, CYP3A4, NAT1 | TSHR 3640/4885FFAR1 2450/4885FFAR4 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.