Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26608285 | 0.80 | ALDH1A1 (0.38) | POLBKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL26601698 | 0.80 | POLB (0.32) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10639171 | 0.69 | PDE10A (0.34) | KMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL5946432 | 0.67 | CYP3A4 (0.40) | — | |
| SCHEMBL1397057 | 0.67 | ALDH1A1 (0.39) | HTR1ADRD2 | |
| SCHEMBL25761499 | 0.67 | ALDH1A1 (0.45) | POLBKMT2AMEN1SMN1; SMN2HTR1A | |
| SCHEMBL11664937 | 0.67 | NOS3 (0.32) | KMT2AMEN1 | |
| SCHEMBL8509915 | 0.65 | POLB (0.36) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL62021 | 0.65 | POLB (0.53) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10958985 | 0.65 | HSP90AB1 (0.36) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59101469-A | — | — | None | — | — | JP | disclosed |
| JP-S59101469-A | PREPARATION OF 5-METHYLTHIOPYRIMIDINE DERIVATIVE | MITSUI TOATSU CHEM INC | 1984-06-12 | — | — | JP | disclosed |