SCHEMBL11034682

SCHEMBL11034682

BrC(Br)C(Br)Br.CCc1cccc(N)c1CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
TAAR1 Q96RJ0 2/20 0.34
HTR1A P08908 1/20 0.34
DHFR P00374 1/20 0.34
PARP1 P09874 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
PIK3CA P42336 1/20 0.33
ELANE P08246 1/20 0.33
PDK2 Q15119 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
KCNH2 Q12809 2/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
SCN5A Q14524 1/20 0.32
ESR1 P03372 1/20 0.31
HTT P42858 1/20 0.30
CD44 P16070 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165995 0.90 GABRA1 (0.46) GABRA1GABRB2TAAR1HTR1ADHFR
Hydrochloric Acid SCHEMBL8136588 0.88 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1ADHFR
Ammonia Solution, Strong SCHEMBL7468688 0.88 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1ADHFR
SCHEMBL6436719 0.88 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1ADHFR
SCHEMBL17745129 0.79 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1ADHFR
SCHEMBL2213750 0.79 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1APARP1
SCHEMBL4609225 0.79 GABRA1 (0.42) GABRA1GABRB2TAAR1HTR1ADHFR
Pyrene SCHEMBL5678493 0.79 ALDH1A1 (0.41) GABRA1GABRB2TAAR1HTR1ADHFR
SCHEMBL6308607 0.78 PNMT (0.40) GABRA1GABRB2PARP1CYP3A4TSHR
Methylamine SCHEMBL27545014 0.76 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1ADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4533404-A REACTION PRODUCT OF AROMATIC AMINO COMPOUND AND BROMINATED ALIPHATIC HYDROCARBON NIHON ALMIT KABUSHIKI KAISHA (JP) 1985-08-06 US disclosed
EP-0127993-A2 Soldering fluxes and their production processes NIHON ALMIT KABUSHIKI KAISHA (JP) 1984-12-12 EP disclosed