Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768922 | 0.77 | HSD17B10 (0.53) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL2745305 | 0.77 | CREBBP (0.57) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL4325934 | 0.77 | HSD17B10 (0.53) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL9024189 | 0.77 | HSD17B10 (0.53) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL31542005 | 0.77 | HSD17B10 (0.53) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL24125191 | 0.77 | CREBBP (0.57) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL10735538 | 0.77 | HSD17B10 (0.69) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL8477667 | 0.76 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL8477662 | 0.76 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1POLBALOX15 | |
| SCHEMBL2117385 | 0.76 | HSD17B10 (1.00) | HSD17B10KDM4ETDP1POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535079-A | HYPOTENSIVE, ANTIARRHYTHMIA, ADRENERGIC BLOCKING AGENTS; VASODILATORS | MEDIOLANUM FARMACEUTICI S.R.L. (IT) | 1985-08-13 | — | — | US | disclosed |
| EP-0106816-A2 | Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3-one, their production process, and their pharmaceutical use | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1984-04-25 | — | — | EP | disclosed |