SCHEMBL31542005

SCHEMBL31542005

O=C1Nc2ccccc2SC1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.53
KDM4E B2RXH2 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
POLB P06746 2/20 0.53
ALOX15 P16050 2/20 0.53
GLA P06280 1/20 0.53
USP2 O75604 1/20 0.53
ESR1 P03372 1/20 0.53
THRB P10828 1/20 0.53
HPGD P15428 1/20 0.53
PTPN7 P35236 1/20 0.53
RECQL P46063 1/20 0.53
ESR2 Q92731 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4325934 1.00 HSD17B10 (0.53) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL10352528 0.81 HSD17B10 (0.50) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL28768922 0.77 HSD17B10 (0.53) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL11034753 0.77 HSD17B10 (0.61) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL9024189 0.77 HSD17B10 (0.53) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL24125191 0.77 CREBBP (0.57) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL2745305 0.77 CREBBP (0.57) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL10729385 0.77 HSD17B10 (0.65) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL3626456 0.74 CA2 (0.62) HSD17B10KDM4ETDP1POLBALOX15
SCHEMBL4969852 0.74 MAPT (0.51) HSD17B10KDM4ETDP1POLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064829-A1 A MOLECULAR SCAFFOLD FOR DEPLETING HRPN13 AND A SELECT GROUP OF KEN BOX PROTEINS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-03-27 WO disclosed