Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285401 | 0.81 | CNR2 (0.43) | MEN1KMT2AFAAHTHRATHRB | |
| SCHEMBL9285396 | 0.80 | CYP3A4 (0.37) | TSHRLMNAMEN1KMT2ANR1I2 | |
| SCHEMBL10524299 | 0.80 | CHRNA7 (0.32) | TSHRKDM4EHPGDMEN1KMT2A | |
| SCHEMBL11050326 | 0.76 | — | — | |
| SCHEMBL9676473 | 0.75 | HDAC1 (0.39) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL9435801 | 0.75 | CNR2 (0.45) | TSHRHPGDLMNACYP3A4HDAC6 | |
| SCHEMBL28034042 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL4835391 | 0.72 | CA2 (0.38) | FAAHCA2 | |
| SCHEMBL4763663 | 0.71 | NPC1 (0.42) | TSHRKDM4EHPGDLMNAMEN1 | |
| SCHEMBL2350216 | 0.71 | CA2 (0.41) | FAAHCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046677-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4487626-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4333760-A | ARYLSULFONYLURIDOQUINAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0046677-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-03 | — | — | EP | disclosed |