Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285401 | 0.85 | CNR2 (0.43) | MEN1KMT2ATHRATHRBCNR2 | |
| SCHEMBL11034760 | 0.80 | TSHR (0.34) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL9435801 | 0.79 | CNR2 (0.45) | CYP3A4LMNAHDAC6ALDH1A1CNR2 | |
| SCHEMBL8854278 | 0.79 | CRY1 (0.34) | MEN1KMT2A | |
| SCHEMBL8854255 | 0.79 | ESR1 (0.43) | CYP3A4KMT2AALDH1A1TDP1CA9 | |
| SCHEMBL2842354 | 0.78 | CYP3A4 (0.47) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL10575717 | 0.78 | NPC1 (0.44) | KMT2ATP53ALDH1A1MMP1MMP9 | |
| SCHEMBL27586726 | 0.74 | SIGMAR1 (0.45) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL4835391 | 0.73 | CA2 (0.38) | TP53CES2CES1 | |
| SCHEMBL2350216 | 0.72 | CA2 (0.41) | TP53CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7002758-A | — | — | None | — | — | JP | disclosed |
| JP-H072758-A | NEW BIS(ARYLSULFONYLUREIDO)BENZENE COMPOUND | NEW OJI PAPER CO LTD | 1995-01-06 | — | — | JP | disclosed |