SCHEMBL4835391

SCHEMBL4835391

CCCCCS(=O)(=O)N(S)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.38
FAAH O00519 5/20 0.38
CES1 P23141 3/20 0.36
CES2 O00748 2/20 0.36
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9675522 0.82 FAAH (0.41) FAAHCES1CES2
SCHEMBL2350216 0.80 CA2 (0.41) CA2FAAHCES1CES2TP53
SCHEMBL9285401 0.77 CNR2 (0.43) CA2FAAH
SCHEMBL9285396 0.73 CYP3A4 (0.37) CES1CES2TP53
SCHEMBL11133468 0.72 CA2 (0.48) CA2FAAHTP53
SCHEMBL11034760 0.72 TSHR (0.34) CA2FAAH
SCHEMBL11513325 0.72 CA2 (0.38) CA2FAAHCES1CES2
SCHEMBL2356453 0.70 CA2 (0.33) CA2FAAHCES1CES2TP53
SCHEMBL7593038 0.70 CA2 (0.46) CA2FAAHTP53
SCHEMBL4794021 0.69 CA2 (0.45) CA2FAAHCES1CES2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885200-B1 SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2008-05-21 EP disclosed
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP disclosed
CN-1293060-C Substituted arylsulfonyl (thio) ureas as herbicides BAYER AG (DE) 2007-01-03 CN disclosed
CN-1293060-C Substituted arylsulfonyl (thio) ureas as herbicides BAYER AG (DE) 2007-01-03 CN disclosed
EP-1683789-A1 Substituted arylsulfonyl(thio)ureas as herbicides Bayer CropScience AG (DE) 2006-07-26 EP disclosed
US-20050148467-A1 Heat-sensitive recording material JUJO THERMAL OY (FI) 2005-07-07 US disclosed
CN-1576274-A Substituted arylsulfonyl (thio) ureas as herbicides BAYER AG (DE) 2005-02-09 CN disclosed
CN-1576274-A Substituted arylsulfonyl (thio) ureas as herbicides BAYER AG (DE) 2005-02-09 CN disclosed
US-20050004123-A1 Substituted aryl sulphonyl(thio)ureas used as herbicides BAYER AG (DE) 2005-01-06 US disclosed
US-6838414-B2 Substituted aryl sulphonyl(thio)ureas used as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2005-01-04 US disclosed
CN-1212686-A Substituted arylsulfonyl (thio) ureas as herbicides BAYER AG (DE) 1999-03-31 CN disclosed
EP-0885200-A1 SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES BAYER AG (DE) 1998-12-23 EP disclosed
WO-1997032861-A1 SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-09-12 WO disclosed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP disclosed
EP-0526072-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-09-13 EP disclosed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP disclosed
US-5292711-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-03-08 US disclosed
US-5246906-A Sulfonyl-urea or -thiourea color developer, oil and plasticizer resistant, storage stable OJI PAPER CO., LTD. (JP) 1993-09-21 US disclosed
EP-0526072-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-02-03 EP disclosed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004123-A1 Substituted aryl sulphonyl(thio)ureas used as herbicides DDT, CBR3, TST CA2 1414/4885FAAH 942/4885CES1 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.