SCHEMBL11034847

SCHEMBL11034847

CO[Si](OC(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 10/20 0.41
TDO2 P48775 10/20 0.41
HTT P42858 2/20 0.40
LMNA P02545 2/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SCN1A P35498 3/20 0.35
SCN2A Q99250 3/20 0.35
SCN3A Q9NY46 3/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15052233 0.80 IDO1 (0.37) IDO1TDO2HTTLMNAMAPK1
SCHEMBL28390987 0.79 TSHR (0.33) TSHR
SCHEMBL27596877 0.78 CA4 (0.41) LMNAMAPK1KDM4ESMN1; SMN2CYP1A2
SCHEMBL49008 0.78 CA4 (0.41) LMNAMAPK1KDM4ESMN1; SMN2CYP1A2
SCHEMBL28431726 0.77 IDO1 (0.40) IDO1TDO2HTTLMNAMAPK1
SCHEMBL27743669 0.75 CA4 (0.39) LMNAMAPK1KDM4ESMN1; SMN2CYP1A2
SCHEMBL11588483 0.75 CA1 (0.41) IDO1TDO2HTTLMNAMAPK1
SCHEMBL706592 0.75 ESR1 (0.41) LMNAMAPK1KDM4ESMN1; SMN2CYP1A2
SCHEMBL5420851 0.73 SLC6A2 (0.40) IDO1TDO2LMNAMAPK1KDM4E
SCHEMBL296686 0.73 CA4 (0.38) LMNAMAPK1KDM4ESMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59086665-A None JP disclosed
JP-S5986665-A OIL-MODIFIED ALKYD RESIN PAINT COMPOSITION MITSUBISHI PETROCHEM CO LTD 1984-05-18 JP disclosed