SCHEMBL15052233

SCHEMBL15052233

CO[Si](OC)(OC(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.37
TDO2 P48775 4/20 0.37
CHRM2 P08172 3/20 0.36
ADRA2A P08913 3/20 0.36
CHRM1 P11229 3/20 0.36
SLC6A2 P23975 3/20 0.36
ADRA1A P35348 3/20 0.36
OPRM1 P35372 3/20 0.36
DRD3 P35462 3/20 0.36
SLC6A3 Q01959 3/20 0.36
KCNH2 Q12809 3/20 0.36
HTT P42858 2/20 0.36
CYP2D6 P10635 2/20 0.36
DRD1 P21728 2/20 0.36
HTR1A P08908 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
SCN1A P35498 3/20 0.35
SCN2A Q99250 3/20 0.35
SCN3A Q9NY46 3/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034847 0.80 IDO1 (0.41) IDO1TDO2CHRM2ADRA2ACHRM1
SCHEMBL9485216 0.79 KMT2A (0.32) KMT2A
SCHEMBL7242289 0.79 POLB (0.33) MAPK1SMN1; SMN2KDM4ENPSR1ALDH1A1
SCHEMBL28102831 0.78 LMNA (0.37) SLC6A2SLC6A3HTTCYP2D6LMNA
SCHEMBL37986 0.78 CA4 (0.41) LMNACYP1A2TSHRMAPK1KMT2A
SCHEMBL3338301 0.78 POLB (0.32) TSHRMAPK1SMN1; SMN2KDM4EALDH1A1
SCHEMBL28173753 0.78 POLB (0.32) MAPK1SMN1; SMN2KDM4EALDH1A1
SCHEMBL28173769 0.78 POLB (0.32) SLC6A2SLC6A3CYP2D6SLC6A4CYP1A2
SCHEMBL28431726 0.77 IDO1 (0.40) IDO1TDO2CHRM2ADRA2ACHRM1
SCHEMBL27594753 0.76 POLB (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113614132-A Photocurable resin composition for imprinting, method for producing photocurable resin composition for imprinting, and method for producing patterned body 大日本印刷株式会社 2021-11-05 CN disclosed
EP-2751209-B1 METHODS OF PRODUCING A TITANIUM DIOXIDE PIGMENT AND IMPROVING THE PROCESSABILITY OF TITANIUM DIOXIDE PIGMENT PARTICLES TRONOX LLC (US) 2020-09-30 EP disclosed
CN-103814090-B The method preparing TiO 2 pigment and the method for the machinability improving titanium dioxide pigment particles 特罗诺克斯有限公司 2016-10-05 CN disclosed
EP-2751209-A1 METHODS OF PRODUCING A TITANIUM DIOXIDE PIGMENT AND IMPROVING THE PROCESSABILITY OF TITANIUM DIOXIDE PIGMENT PARTICLES Tronox LLC (US) 2014-07-09 EP disclosed
CN-103814090-A Methods of producing titanium dioxide pigment and improving the processability of titanium dioxide pigment particles TRONOX LLC 2014-05-21 CN disclosed
US-8663518-B2 Methods of producing a titanium dioxide pigment and improving the processability of titanium dioxide pigment particles TRONOX LLC (US) 2014-03-04 US disclosed
WO-2013101838-A1 METHODS OF PRODUCING A TITANIUM DIOXIDE PIGMENT AND IMPROVING THE PROCESSABILITY OF TITANIUM DIOXIDE PIGMENT PARTICLES TRONOX LLC (US) 2013-07-04 WO disclosed
US-20130161856-A1 METHODS OF PRODUCING A TITANIUM DIOXIDE PIGMENT AND IMPROVING THE PROCESSABILITY OF TITANIUM DIOXIDE PIGMENT PARTICLES TRONOX LLC (US) 2013-06-27 US disclosed