Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034895 | 1.00 | MAPT (0.50) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL10987773 | 0.76 | MEN1 (0.41) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL4318524 | 0.73 | GAA (0.43) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL9595515 | 0.73 | MAPT (0.48) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL10993495 | 0.73 | GAA (0.32) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL9603546 | 0.72 | KMT2A (0.41) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL10990642 | 0.70 | MAPT (0.46) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL10990634 | 0.70 | MAPT (0.46) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL9599085 | 0.69 | GAA (0.33) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL9038722 | 0.68 | MAPT (0.43) | MAPTMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | disclosed |