Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595820 | 0.82 | NOS3 (0.36) | KMT2AMEN1MAPTNPSR1CREBBP | |
| SCHEMBL9588376 | 0.79 | KMT2A (0.52) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL9594788 | 0.78 | RAB9A (0.39) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL9595934 | 0.77 | KMT2A (0.45) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL9595952 | 0.77 | KMT2A (0.42) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL10991118 | 0.75 | MAPT (0.33) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL10996793 | 0.75 | MAPT (0.33) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL9038730 | 0.74 | MAPT (0.43) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL9038722 | 0.74 | MAPT (0.43) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL10993495 | 0.74 | GAA (0.32) | KMT2AMEN1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016076-A1 | 3-(1H^_-TETRAZOL-5-YL)-4H^_-PYRIDO[1,2-A^_]PYRIMIDINE-4-ONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |