Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176522 | 0.89 | SMN1; SMN2 (0.34) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7389179 | 0.81 | TNKS (0.33) | TNKSPARP1WNT3ATNKS2PARP2 | |
| SCHEMBL9384614 | 0.78 | TNKS (0.31) | TNKSPARP1WNT3ATNKS2PARP2 | |
| SCHEMBL11108193 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1APAF1NSD2TP53 | |
| SCHEMBL11111028 | 0.74 | APOBEC3A (0.32) | ALDH1A1TNKSPARP1WNT3ATNKS2 | |
| SCHEMBL9878759 | 0.74 | PDE10A (0.43) | — | |
| SCHEMBL9386510 | 0.74 | — | — | |
| SCHEMBL10576181 | 0.74 | TNKS (0.40) | TNKSPARP1WNT3ATNKS2PARP2 | |
| SCHEMBL23586251 | 0.73 | PDE10A (0.38) | — | |
| SCHEMBL9877552 | 0.70 | NSD2 (0.31) | NSD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59141583-A | — | — | None | — | — | JP | disclosed |
| JP-S59141583-A | THIOPYRANOPYRIMIDINE DERIVATIVE AND ITS ACID ADDITION SALT | MARUKO SEIYAKU KK | 1984-08-14 | — | — | JP | disclosed |
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |