Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389179 | 0.81 | TNKS (0.33) | TNKSPARP1WNT3ATNKS2PARP2 | |
| SCHEMBL10569746 | 0.78 | TNKS (0.31) | TNKSPARP1WNT3ATNKS2PARP2 | |
| SCHEMBL11035315 | 0.74 | KDM4E (0.35) | APOBEC3AAPOBEC3GNOS3NOS1NOS2 | |
| SCHEMBL11112029 | 0.74 | PDE4B (0.35) | PDE4BPDE4D | |
| SCHEMBL11102672 | 0.73 | ALDH1A1 (0.35) | PDE4BPDE4DALDH1A1MAPK1 | |
| SCHEMBL11104756 | 0.68 | PDE4B (0.36) | PDE4BPDE4DMAPK1 | |
| SCHEMBL9383054 | 0.68 | HTR2C (0.45) | PDE4BPDE4DALDH1A1 | |
| SCHEMBL10572515 | 0.68 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL11101187 | 0.68 | KMT2A (0.46) | — | |
| SCHEMBL11107458 | 0.68 | SMN1; SMN2 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |