SCHEMBL1103553

SCHEMBL1103553

c1ccc2c(c1)Sc1ccccc1N2c1c2ccccc2c(-c2ccc3ccccc3c2)c2c1cnc1ccccc12

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.39
BCHE P06276 4/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTR2B P41595 2/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR6 P50406 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ACHE P22303 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GPR3 P46089 1/20 0.31
HTR5A P47898 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103441 0.87 TLR7 (0.34) NPSR1KDM4E
SCHEMBL1103555 0.86 MET (0.39) METPIK3CDPIK3CAMTORMEN1
SCHEMBL1103552 0.85 MET (0.36) METPIK3CDPIK3CAMTORNPSR1
SCHEMBL1103550 0.83 MET (0.37) METBCHEPIK3CDPIK3CAMTOR
SCHEMBL1103551 0.83 MET (0.37) METPIK3CDPIK3CAMTORMEN1
SCHEMBL1103607 0.83 BCHE (0.36) METBCHESLC6A3ACHEKDM4E
SCHEMBL1103317 0.81 MAOA (0.35) BCHENPSR1ACHEKDM4EGPR3
SCHEMBL1102955 0.80 CYP17A1 (0.39) BCHEMEN1KMT2ANPSR1HTR2B
SCHEMBL1103190 0.79 BCHE (0.36) BCHEMEN1KMT2ANPSR1HTR2B
SCHEMBL1103549 0.79 MET (0.39) METBCHEPIK3CDPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
EP-2147962-A1 Azaanthracene-derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 MET 4191/4885BCHE 1355/4885PIK3CD 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.