Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752986 | 0.88 | NPC1 (0.67) | FLT3MAOAMAOBLCKNPC1 | |
| SCHEMBL2010000 | 0.86 | MAOA (0.62) | MAOAMAOBLCKNPC1RAB9A | |
| SCHEMBL10509414 | 0.85 | ALDH1A1 (0.64) | FLT3MAOAMAOBLCKNPC1 | |
| SCHEMBL1896215 | 0.85 | LMNA (0.66) | MAOAMAOBLCKNPC1RAB9A | |
| SCHEMBL9990783 | 0.85 | MAOA (0.51) | MAOAMAOBLCKKMT2AADORA2A | |
| SCHEMBL9550369 | 0.81 | FLT3 (0.52) | FLT3MAOAMAOBNPC1RAB9A | |
| SCHEMBL4674251 | 0.80 | LMNA (0.53) | MAOAMAOBLCKNPC1RAB9A | |
| SCHEMBL4675984 | 0.77 | MAOA (0.68) | MAOAMAOBNPC1RAB9AKMT2A | |
| SCHEMBL1367029 | 0.76 | MAOA (0.79) | MAOAMAOBLCKADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL8689066 | 0.74 | LCK (0.50) | MAOAMAOBLCKNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59190985-A | — | — | None | — | — | JP | disclosed |
| JP-S59190985-A | BISBENZOFURAN DERIVATIVE AND ITS PREPARATION | KAKEN PHARMACEUT CO LTD | 1984-10-29 | — | — | JP | disclosed |