Phenol

Phenol

SCHEMBL11035845

CO.Oc1ccccc1.Oc1ccccc1-c1ccccc1Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
BCL2L1 Q07817 1/20 0.45
CYP2A6 P11509 1/20 0.45
GLA P06280 2/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA14 Q9ULX7 1/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29807938 0.87 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
SCHEMBL1022489 0.87 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
SCHEMBL18516201 0.85 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
Phenol SCHEMBL28474560 0.82 CA12 (0.65) ALDH1A1HPGDHSD17B10BCL2L1GLA
SCHEMBL20503649 0.82 CYP2A6 (0.71) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
2-Chlorophenol SCHEMBL2575874 0.78 ALDH1A1 (0.79) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
Ether SCHEMBL28198832 0.77 ALDH1A1 (0.45) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
Phenol SCHEMBL27256946 0.77 CYP2A6 (0.77) ALDH1A1HPGDHSD17B10BCL2L1CYP2A6
Phenol SCHEMBL28427173 0.76 CA12 (0.55) ALDH1A1HPGDHSD17B10BCL2L1GLA
SCHEMBL28234020 0.75 ALOX5 (0.54) ALDH1A1HPGDHSD17B10GLACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59095275-A None JP disclosed
JP-S5995275-A PREPARATION OF 1-(O-CHLOROTRITYL)-IMIDAZOLE KOTOBUKI SEIYAKU KK 1984-06-01 JP disclosed