SCHEMBL18516201

SCHEMBL18516201

Oc1ccccc1-c1ccccc1-c1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
HPGD P15428 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
KMT2A Q03164 4/20 0.50
HSD17B10 Q99714 3/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
ALOX15 P16050 2/20 0.50
NFKB1 P19838 2/20 0.50
ALOX12 P18054 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
TSHR P16473 2/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
DPP4 P27487 1/20 0.45
KDM4E B2RXH2 2/20 0.44
GLA P06280 1/20 0.44
LMNA P02545 2/20 0.43
PIK3CA P42336 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29807938 0.97 ALDH1A1 (0.62) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL1022489 0.97 ALDH1A1 (0.62) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL20503649 0.87 CYP2A6 (0.71) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
Phenol SCHEMBL11035845 0.85 ALDH1A1 (0.48) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL986607 0.84 ALDH1A1 (0.63) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL21886351 0.83 ALDH1A1 (0.52) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL7106910 0.81 TSHR (0.62) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL4445751 0.81 ALDH1A1 (0.54) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL1513821 0.81 TSHR (0.62) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10
SCHEMBL671133 0.81 CYP2A6 (0.67) ALDH1A1HPGDSMN1; SMN2KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017026643-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-02-16 WO disclosed