SCHEMBL11035872

SCHEMBL11035872

CCCCCCCCCCCCOC(=O)C(C)OC(=O)c1ccc(Cl)c(NC(C)=O)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
MAPT P10636 2/20 0.48
NPC1 O15118 2/20 0.45
HTT P42858 1/20 0.45
HPGD P15428 2/20 0.44
RECQL P46063 1/20 0.44
LMNA P02545 1/20 0.43
RAB9A P51151 2/20 0.42
CYP1A2 P05177 1/20 0.42
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
RNASEL Q05823 1/20 0.38
TSHR P16473 1/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11465492 0.88 ALDH1A1 (0.63) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL8930408 0.86 MAPT (0.43) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL8930406 0.86 MAPT (0.43) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL9297019 0.85 NPC1 (0.47) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL8996649 0.84 KMT2A (0.44) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL6161836 0.82 ALDH1A1 (0.43) ALDH1A1MAPTNPC1LMNARAB9A
SCHEMBL6161842 0.82 ALDH1A1 (0.49) ALDH1A1MAPTNPC1HPGDLMNA
SCHEMBL11481987 0.82 ALDH1A1 (0.41) ALDH1A1MAPTNPC1LMNARAB9A
SCHEMBL8425344 0.81 HPGD (0.54) ALDH1A1MAPTNPC1HTTHPGD
SCHEMBL11481988 0.80 ALDH1A1 (0.41) ALDH1A1MAPTNPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159911-A1 Silver halide photographic material KONICA CORPORATION (JP) 1985-10-30 EP disclosed