Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037532 | 1.00 | PPARG (0.59) | PPARGPPARAMMP9MMP8PYGL | |
| SCHEMBL10668355 | 1.00 | PPARG (0.59) | PPARGPPARAMMP9MMP8PYGL | |
| SCHEMBL10668352 | 1.00 | PPARG (0.59) | PPARGPPARAMMP9MMP8PYGL | |
| SCHEMBL19520895 | 0.85 | MMP9 (0.55) | MMP9MMP8PYGLCYP2C9SLC1A2 | |
| SCHEMBL19520896 | 0.85 | MMP9 (0.55) | MMP9MMP8PYGLCYP2C9SLC1A2 | |
| SCHEMBL25139519 | 0.84 | MMP9 (0.55) | MMP9MMP8PYGLCYP2C9SLC1A2 | |
| SCHEMBL9556633 | 0.84 | MMP9 (0.55) | MMP9MMP8PYGLCYP2C9SLC1A2 | |
| SCHEMBL10421483 | 0.83 | CTSL (0.56) | MMP9MMP8CYP2C9RAB9AMEN1 | |
| SCHEMBL1132569 | 0.83 | CTSL (0.56) | MMP9MMP8CYP2C9RAB9AMEN1 | |
| SCHEMBL11573515 | 0.83 | CTSL (0.56) | MMP9MMP8CYP2C9RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |