Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600220 | 0.83 | CYP2C9 (0.61) | TDP1POLBCYP1A2GAACYP2C9 | |
| SCHEMBL7737633 | 0.81 | KMT2A (0.47) | TDP1TSHRPOLBCASP6LMNA | |
| SCHEMBL21939298 | 0.81 | TSHR (0.50) | TDP1TSHRPOLBCASP6LMNA | |
| SCHEMBL9475894 | 0.81 | CYP1A2 (0.55) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL23615905 | 0.80 | KMT2A (0.67) | TDP1TSHRPOLBCYP1A2GAA | |
| SCHEMBL29587530 | 0.78 | KMT2A (0.64) | TDP1TSHRPOLBCYP1A2GAA | |
| SCHEMBL9862167 | 0.78 | KMT2A (0.64) | TDP1TSHRPOLBCYP1A2GAA | |
| SCHEMBL15331005 | 0.78 | ALDH1A1 (0.59) | TDP1TSHRPOLBGAALMNA | |
| SCHEMBL4262556 | 0.76 | CYP1A2 (0.77) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL3666480 | 0.75 | AKR1C3 (0.63) | TSHRCYP1A2LMNAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | disclosed |