Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939298 | 0.85 | TSHR (0.50) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11036110 | 0.81 | TDP1 (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL15331005 | 0.81 | ALDH1A1 (0.59) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL23615905 | 0.81 | KMT2A (0.67) | KMT2ATSHRLMNAPOLBCASP6 | |
| SCHEMBL8214859 | 0.79 | TSHR (0.53) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL6056011 | 0.78 | PTGS2 (0.49) | TSHRHSD17B10NPC1USP2RAB9A | |
| SCHEMBL5015515 | 0.78 | PTGS2 (0.49) | TSHRHSD17B10NPC1USP2RAB9A | |
| SCHEMBL3026188 | 0.78 | CALM1 (0.51) | KMT2ATSHRMEN1LMNAHSD17B10 | |
| SCHEMBL1245905 | 0.78 | TSHR (0.69) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10455068 | 0.76 | TSHR (0.50) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414001-B2 | Ether and amide compounds preparation thereof composition containing same and use thereof as antidiadetics | KOTOBUKI PHARMACEUTICAL CO. LTD. (JP) | 2002-07-02 | — | — | US | disclosed |