Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24555361 | 1.00 | NPC1 (0.54) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24555364 | 0.90 | NPC1 (0.52) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15722747 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16705693 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL23185863 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15722637 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18369556 | 0.79 | NPC1 (0.51) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29632810 | 0.78 | L3MBTL1 (0.51) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15722636 | 0.77 | NPC1 (0.52) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5380991 | 0.76 | ALOX15 (0.45) | NPC1RAB9AALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59137454-A | — | — | None | — | — | JP | disclosed |
| JP-S59137454-A | HYDRAZONE COMPOUND | RICOH CO LTD | 1984-08-07 | — | — | JP | disclosed |