Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913879 | 0.91 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL5779410 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL10866643 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL11023715 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL6903795 | 0.75 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL6902966 | 0.73 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL11020193 | 0.72 | MAPKAPK3 (0.38) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL6898305 | 0.71 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL9044874 | 0.71 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL11025809 | 0.70 | MAPKAPK3 (0.45) | ALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195135-A1 | A process for the preparation of quinoline carboxylic acid derivatives | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1986-09-24 | — | — | EP | disclosed |