Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367467 | 0.86 | DRD2 (0.57) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL27402876 | 0.79 | DRD2 (0.49) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL7365851 | 0.78 | ACHE (0.62) | DRD2DRD3 | |
| SCHEMBL5659037 | 0.75 | DRD2 (0.65) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL6226262 | 0.75 | DRD2 (0.65) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL14698020 | 0.75 | DRD2 (0.65) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL7935881 | 0.73 | DRD2 (0.61) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL11036699 | 0.73 | DRD2 (0.91) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL10834524 | 0.73 | DRD2 (0.61) | DRD2DRD3MEN1NPC1RAB9A | |
| SCHEMBL6927206 | 0.73 | DRD2 (0.61) | DRD2DRD3MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |