SCHEMBL11036755

SCHEMBL11036755

O=C(NC(=O)c1ccccc1Cl)Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
POLB P06746 2/20 0.60
PKM P14618 1/20 0.60
GCGR P47871 1/20 0.60
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MAPT P10636 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
PYGL P06737 6/20 0.57
PLCG2 P16885 1/20 0.56
DHODH Q02127 1/20 0.56
FADS1 O60427 1/20 0.55
ATM Q13315 1/20 0.54
CYP1A2 P05177 1/20 0.54
HPGD P15428 1/20 0.54
CYP2C19 P33261 1/20 0.54
PCTP Q9UKL6 1/20 0.52
P2RY1 P47900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840342 0.88 NPC1 (0.60) RAB9ANPC1POLBPKMGCGR
SCHEMBL28596892 0.87 FADS1 (0.71) RAB9ANPC1POLBMEN1KMT2A
SCHEMBL8840248 0.86 RAB9A (0.59) RAB9ANPC1POLBPKMGCGR
SCHEMBL10617761 0.86 NPC1 (0.59) RAB9ANPC1POLBPKMGCGR
Chlorbenzuron SCHEMBL5177776 0.86 GCGR (0.68) RAB9ANPC1POLBPKMGCGR
SCHEMBL8840275 0.85 POLB (0.57) RAB9ANPC1POLBPKMGCGR
SCHEMBL8840339 0.85 TDP1 (0.59) RAB9ANPC1POLBPKMGCGR
SCHEMBL9739800 0.83 GCGR (0.65) RAB9ANPC1POLBPKMGCGR
SCHEMBL10705754 0.82 GCGR (0.64) RAB9ANPC1POLBPKMGCGR
SCHEMBL304416 0.81 POLB (0.69) RAB9ANPC1POLBPKMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59212462-A None JP disclosed
JP-S59212462-A BENZOYLUREA DERIVATIVE AND INSECTICIDE KUMIAI CHEM IND CO LTD 1984-12-01 JP disclosed