Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250191 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KMT2AHSD17B10KDM4EUSP2 | |
| SCHEMBL16535021 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL1720792 | 0.82 | KDM4E (0.56) | ALDH1A1KMT2AHSD17B10KDM4ELMNA | |
| Methyl Nicotinate SCHEMBL29386553 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KMT2AHSD17B10LMNATSHR | |
| Methyl Nicotinate SCHEMBL24566 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KMT2AHSD17B10LMNATSHR | |
| SCHEMBL28000 | 0.81 | TSHR (0.63) | ALDH1A1KMT2AHSD17B10KDM4ELMNA | |
| Methyl Nicotinate SCHEMBL820747 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KMT2AHSD17B10LMNATSHR | |
| SCHEMBL29363206 | 0.81 | TSHR (0.63) | ALDH1A1KMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL27840685 | 0.81 | TSHR (0.63) | ALDH1A1KMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL30509674 | 0.81 | KMT2A (0.59) | ALDH1A1KMT2AKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153279-B2 | Organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2012-04-10 | — | — | US | disclosed |
| US-7888863-B2 | Organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2011-02-15 | — | — | US | disclosed |
| US-7888863-B2 | Organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2011-02-15 | — | — | US | disclosed |
| US-20100033083-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2010-02-11 | — | — | US | disclosed |
| US-20090260686-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-10-22 | — | — | US | disclosed |
| US-20090260686-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-10-22 | — | — | US | disclosed |
| CN-1045962-C | Pyridopyridazinone or pyridinopyridazinethione compounds, intermediates for their preparation, pharmaceutical compositions containing them and their use | SYNTEX INC (US) | 1999-10-27 | — | — | CN | disclosed |
| CN-1088927-A | Benzo and pyrido pyridazinone and pyridazinthione compounds | SYNTEX A INC (US) | 1994-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090260686-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | OCIAD1, OCIAD2, FZD7 | ALDH1A1 706/4885KMT2A 4000/4885HSD17B10 1527/4885 |
| US-20100033083-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | ORMDL3, OCIAD2, OCIAD1 | ALDH1A1 1015/4885KMT2A 3930/4885HSD17B10 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.