Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037152 | 0.91 | TSHR (0.49) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28592481 | 0.85 | TSHR (0.43) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8378769 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAF2PRSS1PRSS2 | |
| SCHEMBL28656162 | 0.77 | DHFR (0.59) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28278748 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2TDP1ALDH1A1LMNAGAA | |
| SCHEMBL11244972 | 0.74 | F2 (0.50) | TSHRTDP1ALDH1A1LMNAF2 | |
| Sulfacetamide SCHEMBL28653550 | 0.74 | SMN1; SMN2 (0.78) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7607789 | 0.73 | TSHR (0.52) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL31386568 | 0.73 | TSHR (0.52) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL27588753 | 0.72 | CA1 (0.43) | TSHRDHFRSMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527226-A | Method for controlling content of ACH in acid in process of preparing acesulfame potassium | 南通醋酸化工股份有限公司 | 2021-10-22 | — | — | CN | disclosed |