Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037157 | 1.00 | FPR2 (0.45) | FPR2F2F7F3AADAT | |
| Bromide SCHEMBL10668746 | 0.99 | FPR2 (0.45) | FPR2F2F7F3AADAT | |
| Bromide SCHEMBL10668756 | 0.99 | FPR2 (0.45) | FPR2F2F7F3AADAT | |
| SCHEMBL10511510 | 0.80 | ALDH1A1 (0.56) | FPR2ALDH1A1PKMHSD17B3NPSR1 | |
| SCHEMBL197585 | 0.79 | ACE (0.55) | F2F7F3NPSR1MEN1 | |
| SCHEMBL197912 | 0.79 | ACE (0.55) | F2F7F3NPSR1MEN1 | |
| SCHEMBL197586 | 0.79 | ACE (0.55) | F2F7F3NPSR1MEN1 | |
| Bromide SCHEMBL7442458 | 0.78 | ACE (0.54) | F2F7F3NPSR1KMT2A | |
| Bromide SCHEMBL7442462 | 0.78 | ACE (0.54) | F2F7F3NPSR1KMT2A | |
| SCHEMBL10511211 | 0.78 | FPR2 (0.45) | FPR2ALDH1A1PKMNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156455-A2 | Condensed seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-02 | — | — | EP | disclosed |