Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.69 |
| ▸ | PGR | P06401 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | AR | P10275 | 2/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.69 |
| ▸ | TNF | P01375 | 1/20 | 0.69 |
| ▸ | IL6 | P05231 | 1/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.69 |
| ▸ | GLUL | P15104 | 1/20 | 0.69 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753162 | 1.00 | NR3C1 (0.69) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL26139858 | 1.00 | NR3C1 (0.69) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL7871111 | 1.00 | NR3C1 (0.69) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL11040065 | 1.00 | NR3C1 (0.69) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL26139850 | 0.97 | NR3C1 (0.65) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL26139861 | 0.97 | NR3C1 (0.65) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL1513745 | 0.91 | HIF1A (0.70) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL147512 | 0.90 | PGR (0.69) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL21641269 | 0.87 | HIF1A (0.59) | NR3C1HIF1APGRCYP3A4HSD17B10 | |
| SCHEMBL21641270 | 0.87 | HIF1A (0.59) | NR3C1HIF1APGRCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123485-A1 | Colon-specific prodrug, the preparation and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-10-31 | — | — | EP | claimed |
| WO-1984004041-A1 | COLON-SPECIFIC DRUG DELIVERY SYSTEM | UNIV CALIFORNIA (US) | 1984-10-25 | — | — | WO | claimed |
| EP-0123485-A1 | Colon-specific prodrug, the preparation and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-10-31 | — | — | EP | disclosed |
| WO-1984004041-A1 | COLON-SPECIFIC DRUG DELIVERY SYSTEM | UNIV CALIFORNIA (US) | 1984-10-25 | — | — | WO | disclosed |