SCHEMBL11037286

SCHEMBL11037286

C=CCNCc1ccccc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
TSHR P16473 2/20 0.36
CYP2D6 P10635 1/20 0.36
HIF1A Q16665 1/20 0.36
MAPT P10636 1/20 0.36
FDPS P14324 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 3/20 0.35
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ALOX15 P16050 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129001 0.81 TSHR (0.52) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL1083028 0.81 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL13468977 0.80 FDPS (0.38) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29259179 0.79 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL6267156 0.79 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL21387588 0.79 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL6337418 0.78 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL6337416 0.78 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL6270650 0.78 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E
SCHEMBL14292004 0.77 MPO (0.49) SLC6A2SLC6A4SLC6A3ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-4512929-A POLYURETHANE MONOMERS, PLANT SAFENING AGENT BASF AKTIENGESELLSCHAFT (DE) 1985-04-23 US disclosed