Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29259179 | 0.98 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL22252237 | 0.82 | PNMT (0.39) | SLC6A2SLC6A4SLC6A3KDM4EPNMT | |
| SCHEMBL11037286 | 0.81 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25491548 | 0.77 | CHRM2 (0.55) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL8018072 | 0.77 | TSHR (0.67) | SLC6A4KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL14292004 | 0.77 | MPO (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1CYP2D6 | |
| SCHEMBL1110921 | 0.77 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL18567145 | 0.76 | ADH1B (0.52) | KDM4EALDH1A1PNMTTSHRCYP2D6 | |
| SCHEMBL11329920 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL8590547 | 0.74 | MC5R (0.53) | KDM4EALDH1A1KMT2ACA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771727-B2 | Microfluidized oil-in-water emulsions and vaccine compositions | ZOETIS LLC (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2269644-A2 | Microfluidized oil-in-water emulsions and vaccine compositions | Pfizer Products Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| US-20100173854-A1 | Microfluidized Oil-in-water Emulsions and Vaccine Compositions | PHARMACIA & UPJOHN COMPANY LLC (US) | 2010-07-08 | — | — | US | disclosed |
| EP-1742659-A1 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | Pfizer Products Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| US-7122191-B2 | Microfluidized oil-in-water emulsions and vaccine compositions | PFIZER INC. (US) | 2006-10-17 | — | — | US | disclosed |
| WO-2005097181-A1 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | PFIZER PRODUCTS INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050220814-A1 | Microfluidized oil-in-water emulsions and vaccine compositions | ZOETIS SERVICES LLC | 2005-10-06 | — | — | US | disclosed |
| US-20040258701-A1 | Microfluidized oil-in-water emulsions and vaccine compositions | PFIZER INC. | 2004-12-23 | — | — | US | disclosed |
| US-4395394-A | POTENTIATION; IMMUNOLOGY | PFIZER INC. (US) | 1983-07-26 | — | — | US | disclosed |
| US-4395394-A | POTENTIATION; IMMUNOLOGY | PFIZER INC. (US) | 1983-07-26 | — | — | US | disclosed |
| US-4310550-A | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310550-A | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |